Dear Sir or Madam, This is Yuhong Zha from the Kihara Bioinformatics Laboratory. We are currently developing a Chimera extension to implement our MAINMAST algorithm. However, when I update my Chimera to the newest version, I started to get permission errors. I'm using a Mac. In our extension, we have some code involving editing files like "os.remove(filename)". However, after the update, the extension receives error "Operation not permitted" when executing those lines. I think one possible reason might be improper updating steps. After the update, I started Chimera directly from installer instead of drag the icon to my folder. Then this error occurs. Later, even when I deleted the Chimera by dragging it to trash and deleting trash, and then re-download and install Chimera, the error still occurs. We have 2 Mac made the update but only one of them has this error. Do you have any clue why this happens? Thank you in advance for your help and looking forward to your reply! If there is any question regarding our extension, please let me know! Best, Yuhong Zha, Kihara Bioinformatics Laboratory, Department of Biological & Computer Science at Purdue University
