Hi John, What hardware ChimeraX needs depends entirely on the data you want to look at and how you want to visualize it.  For example, if you want to use a VR helmet, you'll need a PC with high end graphics hardware.  But if you're looking at normal proteins, then almost any recent computer will do.  For your specific questions, ChimeraX's speed is usually dominated by the single core CPU performance (including the speed of main memory) and the speed of the storage.  The exceptions are VR, where high end GPUs are needed for speed, large models, where more GPU memory  and speed are needed, and high resolution displays which need more GPU memory.   For main memory, 8-64 GB, and for disk memory, reserve 1GB for ChimeraX. For some previous answers, see: https://www.rbvi.ucsf.edu/pipermail/chimerax-users/2018-July/000271.html, https://www.rbvi.ucsf.edu/pipermail/chimerax-users/2020-October/001585.html. tl;dr -- buy a gaming computer.     HTH,     Greg On 5/6/2021 3:20 PM, John Joshua Gutierrez wrote:

Dear Chimera Developers,

Just a quick question regarding the hardware that Chimera/ChimeraX needs. Are these programs CPU and/or GPU heavy? How much memory is recommended? Is the program storage heavy? Essentially, what are the specs needed to run Chimera/ChimeraX comfortably?

Thank you for your time, John

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