Good night,
I would like to construct a human DDX3 homology model in its closed conformation. However, I can not perform a proper alignment. I target the sequence Uniprot ID: O00571 and as models the PDB structures: 2I4I and 2DB3. However, the generated models present
unsatisfactory results in terms of their quality. Attached is the image of the alignment.
Can you help me???


Att.
Alisson Felipe de Oliveira
Farmacêutico
CRF/RS: 18468
Mestrando em Ciências Farmacêuticas - UNIPAMPA