Hi all

I'd like to know if it is possible to change the protonatation state of only one particular residue (histidine) in my protein..
I've been trying to do it using addh tool but with no success, I think it can only work with the protein as a whole, isn' it ? 

Please, any suggestion is welcomed

Sergio
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Sergio Garay
Dr. en Ciencias Biológicas
Facultad de Bioquimica y Cs. Biológicas
Universidad Nacional del Litoral
Santa Fe - Argentina
C.C. 242 - Ciudad Universitaria - C.P. S3000ZAA
Argentina
Ph. +54 (342) 4575-213
Fax. +54 (342) 4575-221