Hi Jean-Francois, In a previous message I suggested looking at the Chimera Preferences dialog, category Preferences, to see where the preferences file is saved. But I don't recommend changing that setting. Changing the setting only changes where Chimera preferences are saved for the current session. Next time you start Chimera it will not use that location unless it is the first preferences file Chimera finds. Why not? Because Chimera can only remember settings by placing them in the preferences file so it does not save the location of the preferences file even if you press the Save button on the dialog because it would not be useful. I believe Chimera looks in the 3 places listed in that menu in the listed order (preferences, .chimera/preferences, $HOME/.chimera/preferences) and uses the first location where the file exists. So if you have a file called preferences in the directory where Chimera starts and you change the menu setting to ".chimera/preferences" then any new preference settings will occur in ".chimera/preferences". But next time you start you will still get the settings from the preferences file in the start-up directory and not the newer ones in file ".chimera/preferences". This is so confusing I am going to report it as a bug. Tom