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Hi Hernando,
Did the graphics driver change?  This is probably a graphics driver bug -- it sounds like the same thing two other people reported this month, and we've just been advising people to update the graphics driver to the latest version, as in this post:

<https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fplato.cgl.ucsf.edu%2Fpipermail%2Fchimera-users%2F2021-December%2F018247.html&amp;data=04%7C01%7Chernando.sosa%40einsteinmed.edu%7Ca913fd40e8e44c26bea608d9ba8bc413%7C9c01f0fd65e040c089a82dfd51e62025%7C0%7C0%7C637745931723935783%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000&amp;sdata=8BPhn8HW%2Be5ddEDIlw0YFVnr5wHwVNNwOmiAMlO6SVQ%3D&amp;reserved=0>

I hope this helps,
Elaine
-----
Elaine C. Meng, Ph.D.
UCSF Chimera(X) team
Department of Pharmaceutical Chemistry
University of California, San Francisco

> On Dec 8, 2021, at 12:14 PM, Hernando J Sosa via Chimera-users <chimera-users@cgl.ucsf.edu> wrote:
>
> Dear Chimera,
>
>  I cannot open Chimer anymore in a computer (Windos10 64) where it was running until yesterday. I tried with no success  reinstalling the program and installing the latestChimera  daily release.
>
> The error that I get at startup says:
>
> <image.png>
>
> If I start in debug mode I get the following error in a command window:
>
> Cannot execute 'gzip': no automatic decompression of .Z files
>
> initializing general preferences
> loading Tix
> initializing graphics
> Return code: -1073741819
>
> How can I resolve this issue?
>
> Thanks
>
> Hernando