Dear Sir,

I am a beginner in  the field of molecular docking. However, I started doing it using Chimera Vina. UCSF Chimera 1.13rc provides the interface while AutoDock Vina does the docking part.

For a couple of cases I have found that inspite of keeping all the parameters same, the best obtained dock scores are coming different for each individual job-run. Is it so because it is a stocastic method? With such different dock scores, what should I do?

I will be extremely grateful of you can kindly address this issue.

Thanking you in advance,

Best regards


--
Prabuddha Bhattacharya