
Chimera is free for noncommercial use, see the homepage: <http://www.cgl.ucsf.edu/chimera/index.html> You can use the Rotamers tool (under Tools... Structure Editing in the Chimera menu) or the command "swapaa" to mutate an amino acid. There is also a Minimize Structure tool (also under Tools... Structure Editing) and a "minimize" command. To show the command line, choose Favorites... Command Line from the menu. For details about using a tool, click the Help button on its dialog. To see the manual page for a command, enter "help [command]", for example: help swapaa You can also search the help (Help... Search Documentation) and take a look at the tutorials (Help... Tutorials). Elaine ----- Elaine C. Meng, Ph.D. UCSF Computer Graphics Lab (Chimera team) and Babbitt Lab Department of Pharmaceutical Chemistry University of California, San Francisco On Dec 13, 2009, at 5:22 AM, gytjyb wrote:
hello! i am a fleshman for this software! can you tell me about this software ,if all the thing is free? how can i minimize a energy and refine for a protein structure? i also want to do a mutation,how can i do? thank you very much!