Well, we are hardly experts on running Chimera in a VM.  Googling around, it seems that downgrading your VirtualBox "guest additions" may solve the problem, as per:

OpenGL, Ubuntu in a VirtualBox | SGrottel

--Eric

                        Eric Pettersen
                        UCSF Computer Graphics Lab
                        http://www.cgl.ucsf.edu

On Jun 17, 2015, at 1:37 PM, Milo Westler <milo@nmrfam.wisc.edu> wrote:

Well I thought I had this figured out, but then my VM broke and I can't get chimera to run in my VM again. 

I am running Vritualbox with a guest system of ubuntu-mate 15.04. I want to be able to use chimera in the VM for a workshop that we are presenting. I have installed the 64 bit version for linux. I get:

~> chimera
pci id for fd 4: 80ee:beef, driver (null)
libGL error: core dri or dri2 extension not found
libGL error: failed to load driver: vboxvideo
libGL error: unable to load driver: swrast_dri.so
libGL error: failed to load driver: swrast
X Error of failed request:  BadValue (integer parameter out of range for operation)
  Major opcode of failed request:  154 (GLX)
  Minor opcode of failed request:  3 (X_GLXCreateContext)
  Value in failed request:  0x0
  Serial number of failed request:  751
  Current serial number in output stream:  752
~>

And when I run:
/opt/UCSF/Chimera64-1.10.1/share> python __main__.py
Chimera is misconfigured.  Please reinstall chimera.


Thanks,

 
--
-- Milo
===================================================
National Magnetic Resonance Facility at Madison
      An NIH-Supported Resource Center

W. Milo Westler, Ph.D.

NMRFAM Director
Senior Scientist
       and
Adjunct Professor
Department of Biochemistry
University of Wisconsin-Madison
DeLuca Biochemistry Laboratories
433 Babcock Drive
Rm B160D
Madison, WI USA 53706-1544
EMAIL: milo@nmrfam.wisc.edu
PHONE: (608)-263-9599
FAX: (608)-263-1722
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