The only thing I can think of here is that maybe you don't already have the Microsoft Visual C++ 2008 SP1 runtime components installed. The 32-bit runtime is available from Microsoft at http://www.microsoft.com/download/en/details.aspx?id=5582, and the 64-bit runtime is available at http://www.microsoft.com/download/en/details.aspx?id=2092. If installing the runtime does fix (or doesn't fix) the problem you're having, please let me know.
I want to setup the chimera 1.5.3 program on windows XP system, but the setup cannot be finished, it retures a error information that says: "Unable to excute file: C:/program file/chimera 1.5.3/bin/pythonn.exe."