Hello chimera-users,

I would like to introduce a-helices into my protein structure ab initio.

Is it possible to do this with chimera?

Another option that I have is to take a-helical pieces of sequence from a different model

and introduce these into the desired model.

Would that be more feasible?

There is a chance I also need to introduce loops and turns ab initio to best localize the

introduced a-helices within my protein structure.

Can you please indicate how can a chimera user build all this ab initio?

Thank you in advance for your time and help,

Chara Spanou

PhD student

University of Cologne