Hi Ajay,
The script referenced in this chimera-users archive message will compute it:

http://www.cgl.ucsf.edu/pipermail/chimera-users/2010-February/004780.html

Extracting the script from that message may be challenging, so I’m attaching it again.  It’s also available from our Chimera Scripts page:

http://plato.cgl.ucsf.edu/trac/chimera/wiki/Scripts

Like it says in the original message you have to assign partial charges before running the script (Tools->Structure Editing->AddCharge, or the “addcharge” command).

—Eric

Eric Pettersen
UCSF Computer Graphics Lab