Hi Pablo, You could try Surfnet (under Tools... Surface/Binding Analysis). http://www.cgl.ucsf.edu/chimera/docs/ContributedSoftware/surfnet/ surfnet.html Outside of Chimera, I personally like the CASTp method; this page links to a server and a publications list: http://sts.bioengr.uic.edu/castp/ Unfortunately, visualization of the CASTp results is more convenient with Pymol (because there is a plugin), but the information can also be used for further visualization in Chimera. I hope this helps, Elaine ----- Elaine C. Meng, Ph.D. meng@cgl.ucsf.edu UCSF Computer Graphics Lab and Babbitt Lab Department of Pharmaceutical Chemistry University of California, San Francisco http://www.cgl.ucsf.edu/home/meng/index.html On Jun 14, 2007, at 11:45 AM, Pablo Emiliano Tomatis wrote:

hello It is possible to find cavities of a protein using chimera? Any hepl??? thanks in advance

-- Lic. Pablo E. Tomatis Instituto de Biología Molecular y Celular de Rosario (IBR) Área Biofísica - Departamento de Química Biológica Fac. Cs. Bioq. y Farm. - U.N.Rosario Suipacha 531 - S2002LRK- Rosario- Argentina Phone:+54-341-4350661/4350596 (ext.110) Fax:+54-341-4390465

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