Hi David, Sorry, multi-chain comparative modelling cannot be done via the Chimera-Modeller interface: <http://www.rbvi.ucsf.edu/chimera/docs/ContributedSoftware/multalignviewer/modeller.html#comparative> You would have to use Modeller directly to access functions such as multi-chain modeling that are not available via the Chimera graphical interface.. One could model a monomer and then open two copies of the model and superimpose them onto the monomers of a template dimer (or apply a known symmetry), but that would not necessarily exclude bad interactions between the copies. Best, Elaine ----- Elaine C. Meng, Ph.D. UCSF Computer Graphics Lab (Chimera team) and Babbitt Lab Department of Pharmaceutical Chemistry University of California, San Francisco On Jan 23, 2015, at 2:00 PM, David Norman (Staff) <d.g.norman@dundee.ac.uk> wrote:

I am trying to model a symmetrical dimer using modeller within Chimera. I cannot work out how to present the alignment and pdb. files in oder to do this. Any hints please. Thanks David