Hi Kaitlyn, This error message says you are trying to write files where you don't have permission to write files. Where it says "Output file" in the dialog, you need to put a pathname to a folder in which you have permission to write files. ** However, as explained in the current documentation, <http://www.rbvi.ucsf.edu/chimera/docs/ContributedSoftware/vina/vina.html> ....the Autodock Vina service through Chimera is no longer available. To use the Autodock Vina tool in Chimera you have to install Autodock Vina yourself on your own computer, and even then, this tool does not allow enough sampling to be useful for most research projects. So instead you may want to use some other docking program or web service (not in Chimera). See these previous posts for discussion and some possible alternatives: <http://plato.cgl.ucsf.edu/pipermail/chimera-users/2020-August/017079.html> <http://plato.cgl.ucsf.edu/pipermail/chimera-users/2020-August/017126.html> I hope this helps, Elaine ----- Elaine C. Meng, Ph.D. UCSF Chimera(X) team Department of Pharmaceutical Chemistry University of California, San Francisco

On Nov 21, 2020, at 5:38 PM, Kaitlyn Merrill <kaitlynmerrill99@gmail.com> wrote:

Hi there,

I have been using Chimera and Autodock Vina through Chimera and started getting this error message whenever I attempt to use the Autodock Vina to dock a ligand. Can you please tell me how to fix this?

Thanks, Kaitlyn

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