Hi Petr, For handling large structures you can try our next generation ChimeraX and use mmCIF file input. http://www.rbvi.ucsf.edu/chimerax/ It so happens I just ported the Chimera structure morph to ChimeraX and it will be in tonight's ChimeraX build. But it is quite slow, could take hours or days on your large system. I am working today on speeding it up. Do your chains mostly move rigidly? We use the Yale Morph Server algorithm to divide chains into semi-rigid segments and this can take eternity to compute. I could add an option that just treats each whole chain as a semi-rigid segment. ChimeraX has few capabilities compared to Chimera, but it handles large structures fast, and has movie recording, so it may be usable for making animations. Tom

On Feb 8, 2017, at 3:31 PM, Petr Leiman wrote:

Dear Chimera Users and Developers,

I am writing to ask if there is a way to animate multiple conformations of a structure containing 144 chains (~300,000 atoms)? Is it possible to read in such a structure into Chimera and preserve chain IDs? We have to use two-letter chain IDs, something that Chimera does not seem to like.

Thank you,

Petr

-------------- Petr Leiman UTMB Galveston, TX77555

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