Hi Cathy, There is not currently a Python routine to save the reply log although I'll see about adding it. For now the following Python function will do the job in your Python script. It would be possible to modify the script to only save the last N lines of the reply log. Let me know if you want that version. Tom def save_reply_log(path): from chimera import dialogs r = dialogs.find('reply') text = r.text.get('1.0', 'end') f = open(path, 'w') f.write(text) f.close()