We are pleased to announce the release of DOCK 6.10. DOCK is a suite of programs for molecular docking. The source code for DOCK 6.10 is available for download and free for academic users at http://dock.compbio.ucsf.edu/DOCK_6/index.htm This is a release of the new genetic algorithm DOCK_GA: Molecular evolution for ligand design. DOCK_GA evolves molecules through breeding, mutation, fitness pressure, and selection. The method leverages powerful sampling, scoring, and searching routines previously implemented into DOCK 6. For full information on what is new in DOCK 6.10, please visit: http://dock.compbio.ucsf.edu/DOCK_6/new_in_6.10.txt Sincerely, The DOCK Team Please visit us at the DOCK Web site. http://dock.compbio.ucsf.edu