Hello,
Sorry no, the lighting presets (flat, full, soft, etc.) are "global" in ChimeraX, meaning that they apply to everything in the scene. 
<https://urldefense.com/v3/__https://rbvi.ucsf.edu/chimerax/docs/user/commands/lighting.html__;!!IKRxdwAv5BmarQ!btXDiW_S0ZI0THUcXQlrgO0lWPBmVZcL75dPstuIrZdt_IV2SA-OPjI4I3HRop3InrnVmx85YjQxiVOgeibG$ >

The only lighting options that can be changed per model are described in the usage for the "lighting model" command, namely: depthCue, directional, shadows and multiShadow:
<https://urldefense.com/v3/__https://rbvi.ucsf.edu/chimerax/docs/user/commands/lighting.html*model__;Iw!!IKRxdwAv5BmarQ!btXDiW_S0ZI0THUcXQlrgO0lWPBmVZcL75dPstuIrZdt_IV2SA-OPjI4I3HRop3InrnVmx85YjQxiZIYPHtQ$ >

You might try to save two separate images from ChimeraX, and then composite them in some other program like Gimp or Photoshop, but I don't know if that would give the appearance that you want.

I hope this helps,
Elaine
-----
Elaine C. Meng, Ph.D.                       
UCSF Chimera(X) team
Resource for Biocomputing, Visualization, and Informatics
Department of Pharmaceutical Chemistry
University of California, San Francisco

> On Aug 19, 2024, at 3:56 PM, ygilron--- via ChimeraX-users <chimerax-users@cgl.ucsf.edu> wrote:
>
> I am trying to render different parts of my model in different styles.
> This is done to emphasize changes in a ligand's force field between different simulations.
> I would like every part of my model to be rendered in "full", and only change the style for my ligand so it will appear either as "flat", with or without a "silhouettes" toggled on.
> Is there an option to do this?
>
> I would like to just render my custom residue "DIO" in the "flat" style.  As you can see from the output it is part of chain 1:
>   " ...Non-standard residues in dt_100_dio_grp1_ph06_traj_comp_center_fit.pdb #1
>    DIO — (DIO)
>    ..."
>
> I tried to use the following command to separately render different parts of a chain:
>    lighting  model #1:DIO    flat 
> from the console:
>> lighting modell #1:DIO flat
>    Expected a keyword
> while selecting DIO fro the select menu and then running :
>    lighting    flat
> changes the style on the whole image.
>
> P.S.
> full output command when I loaded the molecule:
>
> open .\dt_100_dio_grp1_ph06_traj_comp_center_fit.pdb" format pdb coordsets true
> Summary of feedback from opening C:\Users\yis\Desktop\Wenwei Lab\article\first_draft_figs\dt_100_dio_grp1_ph06_traj_comp_center_fit.pdb
> warnings Ignored bad PDB record found on line 1
> REMARK GENERATED BY TRJCONV
> ...
> 1997 messages similar to the above omitted
> dt_100_dio_grp1_ph06_traj_comp_center_fit.pdb title:
> PH06_elaxed_rank_001_alphafold2_translated_100_xyz.pdbqt in water t= 0.00000 step= 0 [more info...]
>
> Chain information for dt_100_dio_grp1_ph06_traj_comp_center_fit.pdb #1
> Chain Description
> ? No description available
> Non-standard residues in dt_100_dio_grp1_ph06_traj_comp_center_fit.pdb #1
> DIO — (DIO)
> FE2 — (FE2)
> dt_100_dio_grp1_ph06_traj_comp_center_fit.pdb has 1001 coordinate sets