Hi Team

I would like to compare to conformations of a protein whose structures have been solved by cryoEM (conf1  with map1 and conf2 with map2)

So I want to have the coordinates *and* the cryoEM maps aligned.

Aligning the two conformations is easy thanks to matchmaker (align conf1 to conf2)

However, I can I align map2 onto conf2 so that I can compare with map1 ?

Basically I would like to do an “inverse” fit into map conf2->map2.

Can I do that ?

Note : I do not want to align map2 ontomap1 because of resolution and structural differences, the superimposition should be done at the coordinate level (actually on a subset of it which is easy in matchmaker).

Thanks !

Prof. Cedric Govaerts, Ph.D.
Universite Libre de Bruxelles
Campus Plaine. Phone :+32 2 650 53 77
Building BC, Room 1C4 203
Boulevard du Triomphe, Acces 2
1050 Brussels
Belgium
http://govaertslab.ulb.ac.be/