Chimera had a script for trajectory smoothing (named smoothMD.py, available here: Scripts – Chimera).  I ported it to ChimeraX and have attached it below.  You run it simply by opening it in ChimeraX.  The very first line of the script controls the “window size” (i.e. how many adjacent frames are used to compute the smoothing).  You have to get tomorrow’s daily build because it uses a ChimeraX function that I just wrote to access the coordinates a certain way in Python.

—Eric