On Oct 23, 2025, at 2:29 PM, Dr. Oscar Perez via ChimeraX-users <chimerax-users@cgl.ucsf.edu> wrote:
Hello ChimeraX Support,
I am trying to use Boltz within ChimeraX to analyze ligand binding affinity, but I cannot find the corresponding option. I do not see any menu item or text that says “Predict Binding Affinity for.”
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When I run an example similar to the one shown in your video for the
HIV protease to evaluate ligand interactions, I obtain the generated 3D structure, but no table with ligand prediction values is produced.
I installed ChimeraX just yesterday, so I assume I am using the latest version. Boltz is installed inside ChimeraX as well.
Could you please advise how I can obtain the ligand interaction values?
Thank you,
Oscar
Oscar Perez-Leal, MD
Associate Professor
Moulder Center For Drug Discovery Research
Temple University School of Pharmacy
3307 N Broad St, Room 556
Philadelphia, PA, 19140
Tel: 215-707-4871