I can confirm: I used the ConSurf server last February and got a ChimeraX session with the results. So they had added this feature before the paper was published.

Guillaume


On 4 Dec 2023, at 19:02, Elaine Meng via ChimeraX-users <chimerax-users@cgl.ucsf.edu> wrote:

Looking at my older notes, I believe I did try their web server back in March 2023 when I first saw this paper, but the download was a Chimera session (not ChimeraX) at that time and their "contact us" webform didn't work.  I don't know if they changed the server to really provide a ChimeraX session since then, or if it was a mistake in the paper.

Elaine

On Dec 4, 2023, at 9:55 AM, Elaine Meng via ChimeraX-users <chimerax-users@cgl.ucsf.edu> wrote:

Hi Martin,
According to this open-access paper, the ConSurf web server <https://consurf.tau.ac.il/> has been upgraded to provide ChimeraX sessions:

Using evolutionary data to make sense of macromolecules with a "face-lifted" ConSurf.
Yariv B, Yariv E, Kessel A, Masrati G, Chorin AB, Martz E, Mayrose I, Pupko T, Ben-Tal N.
Protein Sci. 2023 Mar;32(3):e4582. doi: 10.1002/pro.4582.
PMID: 36718848
<https://onlinelibrary.wiley.com/doi/10.1002/pro.4582>

However, it appears that the ConSurf web server is down for maintenance right now, so I couldn't try it.

Regards,
Elaine
-----
Elaine C. Meng, Ph.D.
UCSF Chimera(X) team
Department of Pharmaceutical Chemistry
University of California, San Francisco

On Dec 4, 2023, at 7:04 AM, martin.brehm--- via ChimeraX-users <chimerax-users@cgl.ucsf.edu> wrote:

Dear ChimeraX developers,

I have a question regarding a potential upgrade of ChimeraX. Would it be possible to include the functionality of ConSurf, a tool to plot the degree of sequence conservation onto a model, into ChimeraX?
The code for this is publically available on GitHub: https://github.com/Rostlab/ConSurf
See this publication for more information: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987940/
Thanks a lot in advance and have a nice day!

Best regards
Martin Brehm



<image001.png>

Martin Brehm – PhD Student
Falk Lab – Max Perutz Labs Vienna
Room 1.624 – Phone +43 14277 74361
martin.brehm@univie.ac.at


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