Glad you got it to work. I think if a ChimeraX plugin says it requires ChimeraX version 12.0 then it will not be allowed to install on an older ChimeraX version like the 12.0 release candidates.

Tom


On Jul 22, 2026, at 2:58 AM, jean-francois.gaucher@u-pariscite.fr wrote:

Hi Tom,

I just reinstalled the latest version of ChimeraX and it's working now. What a mystery!

Thanks for your help.

Have a good day,

Jef


Le 22/07/2026 à 03:02, Tom Goddard a écrit :
Hi Jean-François,

  I don't know why the Install button for ISOLDE using ChimeraX menu Tools / More Tools... does nothing for you.  I suggest updating to the current ChimeraX 1.12 release.  You are using a 1.12 release candidate and the ISOLDE 1.12.0 version is for the ChimeraX 1.12 release.  If that does not help you could download the ISOLDE distribution outside ChimeraX using a web browser from https://cxtoolshed.rbvi.ucsf.edu/apps/chimeraxisolde and then in ChimeraX use the toolshed install command to install the downloaded .whl file.

toolshed install ~/Downloads/chimerax_isolde-1.12.0-cp311-cp311-macosx_11_0_universal2.whl

  Tom

On Jul 21, 2026, at 3:15 AM, jean-francois.gaucher--- via ChimeraX-users <chimerax-users@cgl.ucsf.edu> wrote:

Dear Sir,

I am having trouble downloading version 1.12.0 of ISOLDE from the ChimeraX "toolshed" (using version 1.12rc202606020412 (2026-06-02), installed on an Intel-based MacBook Pro running Sequoia 15.7.7).

When I click the "install" button, nothing happens.

Is this a bug, or have I missed something?

Thank you for developing the ISOLDE software and for your assistance.

Best regards,

Jean-François Gaucher

--
Jean-Francois GAUCHER
Universite de Paris Cite - UFR de pharmacie
Laboratoire Cibles Therapeutiques et Conception de Medicaments
(CiTCoM) UMR 8038 CNRS/UPD
4, av. de l'Observatoire 75270 Paris CEDEX 06
Tel +33(0)1 70 64 94 07     FAX +33(0)1 53 73 99 25
e.mail : jean-francois.gaucher@u-pariscite.fr
https://www.researchgate.net/profile/Jean-Francois_Gaucher/
https://www.citcom.cnrs.fr
orcid 0000-0002-8448-1491

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-- 
Jean-Francois GAUCHER 
Universite de Paris Cite - UFR de pharmacie
Laboratoire Cibles Therapeutiques et Conception de Medicaments
(CiTCoM) UMR 8038 CNRS/UPD
4, av. de l'Observatoire 75270 Paris CEDEX 06
Tel +33(0)1 70 64 94 07     FAX +33(0)1 53 73 99 25
e.mail : jean-francois.gaucher@u-pariscite.fr 
https://www.researchgate.net/profile/Jean-Francois_Gaucher/
https://www.citcom.cnrs.fr
orcid 0000-0002-8448-1491