Dear Ahmed Morsy,
ChimeraX does have a Dock Prep tool,
<
https://rbvi.ucsf.edu/chimerax/docs/user/tools/dockprep.html>
...but it does not have general minimization, sorry, that is still work in progress. See the short list of features not yet in ChimeraX:
<
https://www.rbvi.ucsf.edu/chimerax/progress.html>
There are some features in ChimeraX that can do a little minimization but it is not as complete as in Chimera. See:
<
https://rbvi.ucsf.edu/chimerax/docs/user/tools/mousemodes.html#openmm>
<
https://rbvi.ucsf.edu/chimerax/docs/user/commands/tug.html>
There are dynamics in the ChimeraX ISOLDE plugin, but it may be for advanced users such as cryo-EM structural biologists.
<
https://cxtoolshed.rbvi.ucsf.edu/apps/chimeraxisolde>
I hope this helps,
Elaine
-----
Elaine C. Meng, Ph.D.
UCSF Chimera(X) team
Resource for Biocomputing, Visualization, and Informatics
Department of Pharmaceutical Chemistry
University of California, San Francisco
> On Sep 6, 2024, at 8:01 PM, ahmed morsy <
ahmed_morsy86@yahoo.com> wrote:
>
> Dear Dr. Elaine,
>
>
> Greetings!
>
> I hope this message finds you well.
>
>
> I would like to inquire if ChimeraX offers options for fixing PDB files, specifically for correcting hydrogen bonds and performing energy minimization, in preparation for docking studies.
>
> I look forward to hearing from you and appreciate your guidance.
>
>
> Best regards,
> Ahmed Morsy