This is fixed in the current ChimeraX daily build and release candidate. I accidentally left some Intel Mac test code in earlier builds that caused the problem installing Boltz. Tom
On Dec 7, 2025, at 7:37 AM, Dr. V.N. Balaji via ChimeraX-users <chimerax-users@cgl.ucsf.edu> wrote:
Subject: Bug Report: "Intel Mac" Error Blocking Boltz Install on Windows 11 (NVIDIA 3080 Ti)
Dear ChimeraX Team,
I am writing to report a platform detection bug in the Boltz installer within ChimeraX (Daily Build 1.12.dev202512040236).
When attempting to install Boltz via the boltz install command on a Windows 11 system with a compatible NVIDIA GPU, the installation fails immediately with the following error:
"Boltz requires newer Torch versions that are not available on Intel Macs."
This appears to be a false positive in the installer's logic, erroneously flagging my Windows/x86_64 system as an unsupported Intel Mac.
System Configuration:
OS: Windows 11 Pro (x86_64)
CPU: Intel Core i9-7940X
GPU: NVIDIA GeForce RTX 3080 Ti (12GB VRAM, CUDA 12.x active)
ChimeraX Version: 1.12.dev202512040236 (2025-12-04)
Context & Troubleshooting:
Verified Hardware: I have already successfully installed and verified boltz (v2.2.1) in a standalone PowerShell environment on this same machine; it runs protein-ligand docking with GPU acceleration without issue.
Workarounds Attempted: I have tried running ChimeraX in admin mode, using different daily builds, and attempting to manually intervene with pip, but the internal installer aborts before package retrieval begins due to this platform check.
Request: Could you advise on a command-line flag or manual workaround to bypass this platform check and force a Windows/CUDA installation? Alternatively, if this requires a patch to the installer script to correctly identify Windows environments, please let me know.
Thank you for your assistance.
Best regards,
V.N. Balaji, Ph.D. Computational Chemist Bangalore, India vnbalaji@gmail.com | LinkedIn: vnbalaji _______________________________________________ ChimeraX-users mailing list -- chimerax-users@cgl.ucsf.edu To unsubscribe send an email to chimerax-users-leave@cgl.ucsf.edu Archives: https://mail.cgl.ucsf.edu/mailman/archives/list/chimerax-users@cgl.ucsf.edu/