Hi there,

First of all, thank you for this outstanding piece of software. ChimeraX is truly invaluable and has become an essential tool in my workflow.

As a microscopist working primarily with light microscopy (particularly confocal and light-sheet imaging) I’ve found ChimeraX’s rendering capabilities to be far superior to most tools currently available. I’ve even recommended its use several times on the image.sc forum, especially for rendering high-quality visualizations.

In fact, I recently noticed that there was no #chimerax tag on the forum (surprisingly!) so I took the liberty of creating one. You can find the related post here:

https://forum.image.sc/t/3d-multichannel-surface-rendering-from-z-stacks-napari-script-and-fiji-alternatives/114771/4?u=j_ramirez

While I have this opportunity, I’d like to suggest a feature that I believe would significantly enhance ChimeraX’s utility for large-scale light-sheet microscopy datasets: support for .tiff files larger than 4 GB. 

These large file sizes are quite common in light-sheet acquisitions, and the ability to open them natively in ChimeraX would be a substantial benefit to researchers in this field.

Thank you once again for all the incredible work that goes into developing and maintaining ChimeraX. It’s deeply appreciated.

Warm regards,

J