Hi Jufang,

Thanks for reporting that ChimeraX AlphaFold prediction was broken.  I have fixed it now.  You do not need to update ChimeraX since the fix is in the Colabfold installation script that ChimeraX gets from github each time you run a prediction.  So using your current ChimeraX should now run alphafold predictions without the error.

The problem appears to have been from Google Colab updating their default environment, probably related to the default tensorflow installed.  I updated ChimeraX to use ColabFold 1.6.1 (released March 16, 2026) and use a newer jax 0.7.2 and had to make sure to import tensorflow before installing Colabfold.  Details are in this ChimeraX bug report

https://www.rbvi.ucsf.edu/trac/ChimeraX/ticket/20256

  Tom


On Apr 29, 2026, at 8:07 PM, Chang, Ju Fang via ChimeraX-users <chimerax-users@cgl.ucsf.edu> wrote:

Hi, There,

I think there might be a version compatibility issue, could you please help?

Thank you 

Jufang

 
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