Hi Martin, According to this open-access paper, the ConSurf web server <https://consurf.tau.ac.il/> has been upgraded to provide ChimeraX sessions: Using evolutionary data to make sense of macromolecules with a "face-lifted" ConSurf. Yariv B, Yariv E, Kessel A, Masrati G, Chorin AB, Martz E, Mayrose I, Pupko T, Ben-Tal N. Protein Sci. 2023 Mar;32(3):e4582. doi: 10.1002/pro.4582. PMID: 36718848 <https://onlinelibrary.wiley.com/doi/10.1002/pro.4582> However, it appears that the ConSurf web server is down for maintenance right now, so I couldn't try it. Regards, Elaine ----- Elaine C. Meng, Ph.D. UCSF Chimera(X) team Department of Pharmaceutical Chemistry University of California, San Francisco
On Dec 4, 2023, at 7:04 AM, martin.brehm--- via ChimeraX-users <chimerax-users@cgl.ucsf.edu> wrote:
Dear ChimeraX developers,
I have a question regarding a potential upgrade of ChimeraX. Would it be possible to include the functionality of ConSurf, a tool to plot the degree of sequence conservation onto a model, into ChimeraX? The code for this is publically available on GitHub: https://github.com/Rostlab/ConSurf See this publication for more information: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987940/ Thanks a lot in advance and have a nice day!
Best regards Martin Brehm
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Martin Brehm – PhD Student Falk Lab – Max Perutz Labs Vienna Room 1.624 – Phone +43 14277 74361 martin.brehm@univie.ac.at