Hi Tongqing, You're still using a release candidate version of ChimeraX. If you update to the official ChimeraX 1.10 release version, installation should work correctly. Best wishes, Tristan On Wed, Aug 27, 2025 at 4:35 PM Zhou, Tongqing (NIH/VRC) [E] via ChimeraX-users <chimerax-users@cgl.ucsf.edu> wrote:

Dear All,

I am having problem install ISOLDE on a new MacBook. My ChimeraX version is 1.10rc202505310246 (2025-05-31).

When installing from Toolshed, it says: ERROR: Could not find a version that satisfies the requirement ChimeraX-Core~=1.10.0 (from chimerax-isolde) (from versions: none) ERROR: No matching distribution found for ChimeraX-Core~=1.10.0

Best regards,

*Tongqing*

*Tongqing Zhou, Ph.D.*

Principal Investigator and Chief

Structural Virology and Vaccinology Section

Structural Biology and Structural Bioinformatics Cores

Vaccine Research Center (VRC), NIAID

National Institutes of Health

Building T40, Room 117 (Office)

Building 40, Room 4609B (Lab, shipping)

40 Convent Drive, Bethesda, MD 20892

Office: (301) 761-7068

Cell: (240) 695-0536

*https://www.niaid.nih.gov/research/tongqing-zhou-phd <https://www.niaid.nih.gov/research/tongqing-zhou-phd>*

*tzhou@nih.gov <tzhou@nih.gov>*

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