Sorry, we don't support base debian, only Ubuntu.  The recommendation is that you use the flatpak version.  Or you could install the Ubuntu libgdk-pixbuf2.0-0 before installing ChimeraX.     HTH,     Greg On 1/19/2025 1:22 PM, Francisco Murphy Pérez via ChimeraX-users wrote:

``` root@debian# apt install ./ucsf-chimerax_1.9ubuntu24.04_amd64.deb Note, selecting 'ucsf-chimerax' instead of './ucsf-chimerax_1.9ubuntu24.04_amd64.deb' Some packages could not be installed. This may mean that you have requested an impossible situation or if you are using the unstable distribution that some required packages have not yet been created or been moved out of Incoming. The following information may help to resolve the situation:

Unsatisfied dependencies:  ucsf-chimerax : Depends: libgdk-pixbuf2.0-0 but it is not installable

root@debian# apt install ./libgdk-pixbuf-2.0-0_2.42.12+dfsg-1+b1_amd64.deb Note, selecting 'libgdk-pixbuf-2.0-0' instead of './libgdk-pixbuf-2.0-0_2.42.12+dfsg-1+b1_amd64.deb' libgdk-pixbuf-2.0-0 is already the newest version (2.42.12+dfsg-1+b1). libgdk-pixbuf-2.0-0 set to manually installed. Summary:   Upgrading: 0, Installing: 0, Removing: 0, Not Upgrading: 0 ```

From herehttps://github.com/RBVI/ChimeraX/blob/develop/mkubuntu.py (line 308) looks like  "libgdk-pixbuf2.0-0": "2.40.0+dfsg", is missing a dash?

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