Hi bernd, So I'm surprised that Chimera worked and ChimeraX didn't.  Before this, I've only seen it the other way around.  And it makes sense that installing python didn't help, because ChimeraX uses its own embedded copy.  From the python traceback, it looks like it is hanging when it tries to start up the user interface toolkit.  It is normal for ChimeraX to start up slowly the very first time, so I assume you waited a several minutes.  The delays are caused by your anti-virus software and by the initial runtime linking. If waiting longer for ChimeraX to start doesn't work, then to debug this, please run the Windows "Event Viewer" application (you will need administrative privileges).  Then start up ChimeraX and look for recent events that are related.  If you don't see any events right away, then wait for ChimeraX to completely fail on its own, and then looks at the events.  And please share with me what you find.     HTH,     Greg On 5/5/2021 4:39 AM, Bernd M. Schmidt wrote:

Dear ChimeraX users and coders,

Thanks for the hard work and for providing the community with such great program.

I cannot run Chimera on my desktop PC. After clicking in win10, the cursor indicates something is happening for three seconds, then nothing happens and also no error message or anything appeares Before that, I ran Chimera 1.14rc successfully, since installation of ChimeraX and also with ChimeraX 1.2, this happens. I deinstalled everything and installed first the latest python release (3.9.5), then ChimeraX 1.2. But no change, nothing. Reading the newsgroup suggested running debug mode, finally giving some error message, as seen below.

C:\Program Files\ChimeraX 1.2\bin\lib\site-packages\win32\lib\pywintypes.py:2: DeprecationWarning: the imp module is deprecated in favour of importlib; see the module's documentation for alternative uses   import imp, sys, os Windows fatal exception: access violation

Current thread 0x000023f8 (most recent call first):   File "C:\Program Files\ChimeraX 1.2\bin\lib\site-packages\chimerax\ui\gui.py", line 157 in __init__   File "C:\Program Files\ChimeraX 1.2\bin\lib\site-packages\ChimeraX_main.py", line 577 in init   File "C:\Program Files\ChimeraX 1.2\bin\lib\site-packages\ChimeraX_main.py", line 1015 in <module>   File "C:\Program Files\ChimeraX 1.2\bin\lib\runpy.py", line 87 in _run_code   File "C:\Program Files\ChimeraX 1.2\bin\lib\runpy.py", line 194 in _run_module_as_main

C:\Program Files\ChimeraX 1.2\bin>

Happy for some help.

Many greetings bernd _______________________________________________ ChimeraX-users mailing list ChimeraX-users@cgl.ucsf.edu Manage subscription: https://www.rbvi.ucsf.edu/mailman/listinfo/chimerax-users