Hello,
This was circulated a bit ago but they are still looking. If you are interested please contact Eric Martin (below). I get the feeling they would love to take someone
from UCSF. I know a little bit about the position, so if you have some basic questions you can shoot them to me too.
Job description for Student Internship in Compuational Drug Discovery
Most drug leads are discovered through experimental high-throughput screens, which cost about $1,000,000 and take 6-9 months. Efforts over many years to develop computational “in silico” screens have not resulted in sufficiently accurate models to provide a
practical alternative. Recently, at Novartis, a protein family-based approach has produced models approximating experimental accuracy for the special cases of kinase and serine/cisteine protease enzyme families. These families include many pharmaceutically
important drug targets. This 1-year internship involves learning to train and employ these models on new and existing drug discovery targets. The ideal candidate would understand the physical properties of organic compounds and proteins, and how they can interact,
as well as familiarity with computer programming and running scientific calculations.
Eric Martin ( eric.martin@novartis.com )
Director, Computational Chemistry
Novartis
4560 Horton St.
Emeryville, CA 94608
510-923-3306
--
Alexandra Schnoes, PhD
Program Coordinator, Graduate Student Internships for Career Exploration
Scientist, Babbitt Laboratory
University of California San Francisco
513 Parnassus Ave, S-224
Campus Box 0410
San Francisco, CA 94143
Tel: 415-476-0572
Fax: 415-476-0689
Email:
alexandra.schnoes@ucsf.edu