Hi Andrej, If you decide to post these positions to your email list please have the students and postdocs contact me at the information below. Jared Jared Kaleck Account Executive Klein Hersh International 215-830-9211 Ext. 116 jkaleck@kleinhersh.com www.kleinhersh.com Begin forwarded message:
From: Jared Kaleck <JKaleck@kleinhersh.com> Subject: RE: Referred by Christine Humblet Date: June 4, 2012 11:26:00 AM PDT To: Andrej Sali <sali@salilab.org>
Eli Lilly – Indianapolis, IN Principal Research Scientist/Senior Research Scientist Computational Chemistry The Discovery Chemistry Research and Technology Division at Eli Lilly Company is looking to further enhance the scientific talent base of the organization by identifying individuals with high potential and emerging track record of delivering drug discovery innovation.
Ideal Individuals to Compliment Lilly’s Scientific Team · Talented Ph.D. Computational Chemistry with broad expertise in Computer-Aided Design approaches. · Creative thinking and problem solving skills – ability to bring new ways of applying or pioneering computational approaches and/or new initiatives to facilitate and enhance drug discovery projects. · Proven/emerging scientific leadership abilities – must include leadership work with outside partners and/or scientists from academia. · Ability to influence scientific direction across research sites, discovery functions and teams. A proven desire to make an impact on projects through cross-functional teamwork. · Strong background in medicinal chemistry and lead generation/lead optimization approaches. · Organizational development and mentoring skills. · Excellence in communication and networking skills. · Demonstrated abilities to multi-task. · Entrepreneurial and innovative approach to science; good judgment, risk taking and intuition. · Programming skills (Perl, Python, Pipelining) preferred.
NOVARTIS – Cambridge, MA Computational Chemical-Biology Research Investigator (Ph.D)
Job Description:
A position is available for a highly motivated scientist in the in silico Lead Discovery group of the Center for Proteomic Chemistry platform. This is an exciting opportunity to perform cutting-edge computational research at our Cambridge USA site. The position will be responsible for the development of robust computational hypothesis with a variety of drug discovery project teams for the purposes of lead discovery. You will apply state of the art computational approaches to elucidate the biological profile of small molecules regarding their targets, off-targets and phenotypic outcome via an in-depth understanding of biological networks, systems biology, bioinformatics and cheminformatics
Minimum requirements:
The ideal candidates will possess the following qualifications:
· Ph.D. degree in computational biology, systems biology, bioinformatics, cheminformatics or a related field. · Experience with 'omics analysis (transcriptomics, proteomics, metabolomics, chemogenomics). · Ability to computationally navigate molecular pathways and networks and form hypotheses about compounds, targets, phenotype, and disease associations · Familiarity with compound databases, such as ChEMBL or PubChem, and public bioinformatics databases. · Understanding of up-to-date biological screening paradigms like reporter assays, mRNA signatures, assays for transcription, translation, stability, and post-translational modifications and high content screens. · A solid understanding of quantitative data analysis, data mining and pattern recognition methods. · Ability to work independently and collaborate in multidisciplinary teams locally and globally. · Strong analytical and problem-solving skills and scientific creativity are essential. · Excellent oral and written communication skills and organizational skills are required. · Familiarity with life sciences software (R, Spotfire, Pipeline Pilot, Knime, Cytoscape, GeneGo) is desirable, as is a working knowledge of Relational Databases and SQL.
NOVARTIS – Cambridge, MA Computational Chemistry or Biology Research Investigator (Ph.D)
Job Description: A position is available for a highly-motivated scientist to join a dynamic group in the Center for Proteomic Chemistry/Lead Finding Platform. This is an exciting opportunity to perform cutting-edge research at our Cambridge site. First, you will be responsible for the analysis and development of HTS screening hits to leads. You will apply state of the art chemometric or bioinformatics approaches for the elucidation of the biological profile of small molecules regarding their targets, off-targets and phenotypic outcome. Second, you will provide support, maintenance and further development of key infrastructure related to virtual screening databases and methods, and an internally developed computational services framework.
Minimum requirements: The ideal candidate will possess the following qualifications: • Ph.D. degree in computational biology, bioinformatics, cheminformatics or a related field. • Databases: MySQL, SQL Server and Oracle • Languages: C, C#, Perl, Python, Web Applications and Tools: HTML, ASP.net, • Experience with 'omics data and molecular pathway/network analysis to enhance target knowledge. • Familiarity with compound information databases such as ChEMBL or PubChem. • Understanding of up-to-date biological screening paradigms like reporter assays, mRNA signatures, assays for transcription, translation, stability, and post-translational modifications and high content screens. • A solid understanding of basic statistics and quantitative data analysis, data mining and pattern recognition methods. • Familiarly with PipelipePilot and Knime – a big plus • Ability to both work independently and collaborate in multidisciplinary teams. • Strong analytical and problem-solving skills and scientific creativity are essential. • Excellent oral and written communication skills and organizational skills
Jared Kaleck Account Executive Klein Hersh International 215-830-9211 Ext. 116 jkaleck@kleinhersh.com www.kleinhersh.com