UCSF ChimeraX version 1.12 has been released!
ChimeraX includes user documentation and is free for noncommercial use.
Download for Windows, Linux, and MacOS from:
https://www.rbvi.ucsf.edu/chimerax/download.html
Updates since version 1.11 (December 2025) include:
- OpenFold3 structure prediction
- Boltz server capabilities
- cartoons with straight cylinder helices (alternative to curved tube helices)
- 3D-SNFG glycan representations
- Match->Align to create a multiple sequence alignment from a 3D superposition
- label residues with color-coded grids of amino acid prevalences from
an associated multiple sequence alignment in Profile Grid
- Find Cavities options to include cofactors, restrict search to box
- trajectory clustering
- commands to reproduce clipping plane positions
- Mutation Scores tool for analysis of deep mutational scanning results
For details, please see the ChimeraX change log:
https://www.rbvi.ucsf.edu/trac/ChimeraX/wiki/ChangeLog
On behalf of the team,
Elaine
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Elaine C. Meng, Ph.D.
UCSF Chimera(X) team
Resource for Biocomputing, Visualization, and Informatics
Department of Pharmaceutical Chemistry
University of California, San Francisco
