Hi Sasha, Your ChimeraX version is too old. Please use the current ChimeraX 1.12. The error message you got was "CUDA error: no kernel image is available for execution on the device" and googling that indicates that the PyTorch version used to run Boltz is not compatible with your newer Blackwell Nvidia 5070 Ti. I updated ChimeraX in May 2026 to handle this by installing PyTorch with newer CUDA 12.8 support. So get the newer ChimeraX and reinstall Boltz and it should work. Tom

On Oct 21, 2026, at 5:47 AM, Alexandra Zahradnikova via ChimeraX-users <chimerax-users@cgl.ucsf.edu> wrote:

Dear All, I tried to install Boltz and the installation was completed without errors. When trying to run Boltz, I got an error message that it was not able to use the GPU. After reinstalling the NVIDIA driver, Boltz recognized the gpu, but I got an error again. I then uninstalled Boltz and installed it again – see the attached installation log. However, it again crashed as shown in the zipped log. My gpu card is NVIDIA GeForce RTX 5070 Ti. I would greatly appreciate your help. Best regards Sasha ________________________________________________________________________ Alexandra Zahradníková, PhD Department of Cell Cardiology Institute of Experimental Endocrinology Biomedical Research Centre SAS Dúbravská cesta 9 845 05 Bratislava Slovakia Mobile: +421 908 069 796

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