As noted on the download page, the Windows "Download is a Windows (Inno Setup based) installer. Tested on Windows 10 and Windows 11."  It is a 64-bit distribution and so it goes into "Program Files" by default, the installer lets you pick other locations.  The installation doesn't do anything with the user's AppData folder, but running ChimeraX does.   The download is signed.   InnoSetup installers have silent options -- see https://jrsoftware.org/ishelp/index.php?topic=setupcmdline for details.  The uninstaller, unins000.exe in the installation directory, also has silent options -- see https://jrsoftware.org/ishelp/index.php?topic=uninstcmdline.     HTH,     Greg On 6/9/2026 11:49 AM, McCune, Christopher via ChimeraX-users wrote:

Hi,

I have a few questions regarding the   software.

Is it supported by Windows 11 enterprise?

Is it possible to install it in Program Files or program files x86?

Does the installation do anything with the app data folder?

Are all the executables and dependencies up to data with their code signing?

Are there silent install switches available?

Are there silent uninstall switches available?

Thank you,

Chris McCune Desktop Engineer Department of Medicine, School of Medicine University of Maryland, Baltimore 100 N. Greene St.  RM 201 http://www.medschool.umaryland.edu/medicine/IS/

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