Hello, This was circulated a bit ago but they are still looking. If you are interested please contact Eric Martin (below). I get the feeling they would love to take someone from UCSF. I know a little bit about the position, so if you have some basic questions you can shoot them to me too. Job description for Student Internship in Compuational Drug Discovery Most drug leads are discovered through experimental high-throughput screens, which cost about $1,000,000 and take 6-9 months. Efforts over many years to develop computational “in silico” screens have not resulted in sufficiently accurate models to provide a practical alternative. Recently, at Novartis, a protein family-based approach has produced models approximating experimental accuracy for the special cases of kinase and serine/cisteine protease enzyme families. These families include many pharmaceutically important drug targets. This 1-year internship involves learning to train and employ these models on new and existing drug discovery targets. The ideal candidate would understand the physical properties of organic compounds and proteins, and how they can interact, as well as familiarity with computer programming and running scientific calculations. Eric Martin ( eric.martin@novartis.com<mailto:eric.martin@novartis.com> ) Director, Computational Chemistry Novartis 4560 Horton St. Emeryville, CA 94608 510-923-3306 -- Alexandra Schnoes, PhD Program Coordinator, Graduate Student Internships for Career Exploration Scientist, Babbitt Laboratory University of California San Francisco 513 Parnassus Ave, S-224 Campus Box 0410 San Francisco, CA 94143 Tel: 415-476-0572 Fax: 415-476-0689 Email: alexandra.schnoes@ucsf.edu<mailto:alexandra.schnoes@ucsf.edu> Web: http://gsice.ucsf.edu<http://gsice.ucsf.edu/>