March 2017 - compbio-allhands@cgl.ucsf.edu

[Compbio-allhands] Postdoctoral Position in Computer Aided Drug Design at the University of Notre Dame
by Matthew O'Meara 08 Mar '17

08 Mar '17

Dear all I talked with several of you during the study section last month about a position in the CAMD core I direct here at Notre Dame. I finally got around to putting up the position ad on the CCL (also copied below). If you have strong candidates, (either from your own group or someone else you know) please encourage them to apply. Thanks for your help Olaf =========== Postdoctoral Position in Computer Aided Drug Design at the University of Notre Dame The Warren Family Center for Drug Discovery and Development ( http://drugdiscovery.nd.edu) invites applications for a postdoctoral position in its Computer Aided Molecular Design (CAMD) core facility. Together with the director of the CAMD core, Prof. Olaf Wiest, the successful candidate will work closely with organic, medicinal, and biochemists as well as biologists from Notre Dame and other research institutions to develop models used in the design and development of bioactive compounds. Currently, a number of projects in the areas of cancer, infectious and neurodegenerative diseases as well as rare and neglected diseases are studied in close collaboration with experimentalists from different backgrounds , which allows the rapid testing of the models. After an initial period, this postdoctoral position could be converted into a staff-level position at the University of Notre Dame. Required qualifications - PhD in chemistry or a related field with relevant research experience - Documented experience with two or more of the tools of computer aided drug design such as protein modelling and structure prediction, docking/virtual screening, molecular dynamics simulations, free energy calculations, cheminformatics and databases, ADME/Tox and PD/PK predictions - Demonstrated problem solving abilities - Ability to effectively collaborate with researchers from a variety of backgrounds (organic and medicinal chemistry, chemical, molecular and cell biology, biochemistry), working on multiple projects simultaneously. - Excellent verbal and written communication and presentation skills Responsibilities - Independently conduct research with guidance from the director of the CAMD - Manage interactions with the customers of the CAMD core facility - Plan work load and provide cost estimates and timelines to CAMD customers - Publications in peer review journals, conference talks and posters - Participate in writing of proposals, patents, and publications of CAMD customers - Training and supervision of junior researchers - Acquisition of new projects To apply, please email curriculum vitae, publication list, reference letters (or names and contact information) of at least three individuals familiar with your work, and a statement of research experience to camd(a)nd.edu. Review of application will begin 3/20/2017 and will continue until the position is filled.

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[Compbio-allhands] Fwd: Hands-On Workshop on Computational Biophysics: April 17-21 in Urbana, IL
by Grabe, Michael 06 Mar '17

06 Mar '17

Dear biophysics/comp community. Please see the workshop details on MD simulations below. Best Michael ---------------------------------------------------------- Michael Grabe Associate Professor University of California, San Francisco Cardiovascular Research Institute Department of Pharmaceutical Chemistry 555 Mission Bay Blvd South, Room 452T, MC 3122 San Francisco, California 94143 415-502-2874 (office) 415-476-8173 (fax) Begin forwarded message: From: João Ribeiro KS <jribeiro(a)ks.uiuc.edu<mailto:jribeiro@ks.uiuc.edu>> Subject: Hands-On Workshop on Computational Biophysics: April 17-21 in Urbana, IL Date: March 6, 2017 at 2:49:16 PM PST To: <michael.grabe(a)ucsf.edu<mailto:michael.grabe@ucsf.edu>> Cc: Emad Tajkhorshid <emad(a)life.illinois.edu<mailto:emad@life.illinois.edu>> Dear Michael Grabe, I hope this email finds you well. Please forgive the late notice, but I would like to let you know that the NIH Center for Macromolecular Modeling & Bioinformatics is once again hosting the "Hands-on" Workshop on Computational Biophysics, this time in Urbana, Illinois. Announcement: http://www.ks.uiuc.edu/Training/Workshop/Urbana2017a/ Program: http://www.ks.uiuc.edu/Training/Workshop/Urbana2017a/program.html Instructors: http://www.ks.uiuc.edu/Training/Workshop/Urbana2017a/instructors.html Application Deadline: March 10th, 2017 Enrollment limited to 25 participants. Would you be kind and forward this email to your students and individuals you think that might be interested? Thank you Best wishes Joao Ribeiro Brief description: This workshop will be presented by members of the NIH Center for Macromolecular Modeling & Bioinformatics at Urbana-Champaign. Topics will cover instruction in state-of-the-art molecular dynamics simulation and free energy techniques using NAMD<https://www-s.ks.uiuc.edu/Research/namd/>, bacterial cells simulation with Lattice Microbes<http://www.scs.illinois.edu/schulten/lm/> (LM) and biomolecular visualization and analysis with VMD<https://www-s.ks.uiuc.edu/Research/vmd/>. Morning lecture presentations will introduce fundamental theory and concepts, while afternoon hands-on computer laboratory sessions will allow participants to apply NAMD, LM and VMD directly in a series of guided tutorials. The workshop is designed for all students and researchers in computational and/or biophysical fields who seek to extend their expertise to include biomolecular simulations. Experimentalists and non-specialists are encouraged to attend and will benefit particularly from instruction in the use of QwikMD<https://www-s.ks.uiuc.edu/Research/qwikmd/>, a new teaching software incorporating NAMD and VMD that significantly lowers the learning curve for novice users. -- ……………………………………………………... João Vieira Ribeiro Theoretical and Computational Biophysics Group Beckman Institute, University of Illinois jribeiro(a)ks.uiuc.edu<mailto:jribeiro@ks.uiuc.edu> +1 (217) 3000380

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[Compbio-allhands] 3/9/17 Seminar with Steve Elledge
by Flowers, Nicole 03 Mar '17

03 Mar '17

BBC Graduate Programs Seminar Series Bioinformatics Biophysics Chemistry & Chemical Biology Complex Biological Systems Thursdays, 12 Noon Genentech Hall Auditorium Simulcast to Parnassus Campus S-161 (Please note: A lack of attendance in S-161 within the first 10 minutes of the start time will result in a cancellation of the simulcast.) Steve Elledge Harvard Breaking Bad: How Aneuploidy Drives Cancer March 9, 2017 S. Bandyopadhyay, Host BBC Seminars are supported by the Biophysics, Bioinformatics, and Chemistry & Chemical Biology IFM, Department of Pharmaceutical Chemistry, QBC, HARC Center, the Center for Systems and Synthetic Biology, and the Quantitative Student Group Series. Nicole Takesono Flowers BMI, BP, CCB, & PSPG Graduate Program Assistant UCSF MC 2280 600 16th St. Genentech Hall Room 522 San Francisco, CA 94143 Phone: (415) 502-6518 Fax: (415) 514-1546

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[Compbio-allhands] Fwd: An exciting opportunity for highly talented graduate students and post-docs in your research group
by Brian Shoichet 01 Mar '17

01 Mar '17

FYI. ---------- Forwarded message ---------- From: Timothy A Grese <grese_timothy_a(a)lilly.com> Date: Fri, Feb 24, 2017 at 7:19 AM Subject: An exciting opportunity for highly talented graduate students and post-docs in your research group To: "bshoichet(a)gmail.com" <bshoichet(a)gmail.com> Dear Professor Shoichet, Greetings! I am writing to inform you about an exciting opportunity for highly talented graduate students and post-docs in your research group. You may be aware that Eli Lilly is expanding its research presence on the West Coast at the San Diego Biotechnology facility. As part of this expansion, we are establishing a Medicinal and Synthetic Chemistry group there. We are looking for select individuals to join this group and participate in our mission to provide innovative health care solutions to patients. We are reaching out to select chemistry faculty to help us identify exceptional candidates that meet this need. In addition to classical synthetic and medicinal chemistry approaches, our expanded research center in San Diego will (i) emphasize the application of automation to chemical design, synthesis and testing; (ii) take advantage of the proximity to our world-class structural biology capabilities; (iii) work at the interface of small and large molecule approaches; and (iv) explore unique and innovative methods to collaborate with West Coast research institutions. A job description for the position is included with this letter. We are currently targeting Ph.D. and Post-Doctoral students that will be ready to begin their independent career in 2018. As this is a new research group and the facilities are still being completed, some existing Lilly chemistry leadership and scientists that will work within this group have not yet relocated to San Diego. To facilitate the interview process and ensure that the right individuals are available to meet with candidates, we plan to conduct on-site interviews during a 1-2 week period in June/July of 2017. Therefore we are requesting your assistance to help identify qualified and interested candidates in advance of the normal 2017 recruiting season. Kevin Oberg and Jacqueline Wurst will be accepting CV’s and research summaries until April 17 at the email addresses below. Kevin Oberg, PhD koberg(a)lilly.com Jacqueline Wurst, PhD jwurst(a)lilly.com Where there are sufficient numbers of candidates at a single university or institution, we would like to conduct on-campus interviews in April/May. Alternatively, discussions with potential candidates can be done over the phone before any invitations are made to visit the Lilly San Diego site for in-person interviews. Thank you for your assistance in helping us to identify talented candidates for this exciting opportunity. If you have any questions regarding our new research group or the recruiting process, please feel free to contact me. _____________________________________________________________ *Timothy A. Grese, Ph.D.* Chief Scientific Officer, Discovery Chemistry Research and Technologies Eli Lilly and Company Lilly Corporate Center, Indianapolis IN 46285 U.S.A. 317.276.1356 <(317)%20276-1356> (office) | 317.985-6825 <(317)%20985-6825> (mobile) grese_timothy_a(a)lilly.com | www.lilly.com [image: LillyLogo_EmailSig2.jpg] CONFIDENTIALITY NOTICE: This email message (including all attachments) is for the sole use of the intended recipient(s) and may contain confidential information. Any unauthorized review, use, disclosure, copying or distribution is strictly prohibited. If you are not the intended recipient, please contact the sender by reply email and destroy all copies of the original message. -- Brian Shoichet, Professor, UCSF *http://www.bkslab.org/contact.php <http://www.bkslab.org/contact.php>* By Courtesy: UofT Fac. of Pharmacy

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[Compbio-allhands] RESCHEDULED: 3/8 ICHS Seminar Series with Jure Leskovec
by Rizk-Jackson, Angela 01 Mar '17

01 Mar '17

Hello All, Due to a conflict with the recently scheduled Biohub Investigator orientation meeting, Jure Leskovec will not be available to give his talk as part of the ICHS Seminar Series set for March 8 at 2pm. We are working with Jure to reschedule the seminar for sometime in mid-late May. Please remove this event from your calendar and look for a notification of the revised date/time in the coming days. Apologies for any inconvenience. Best, Angela Angela Rizk-Jackson, Ph.D. Director of Operations Institute for Computational Health Sciences University of California, San Francisco (415) 514-0537 Angela.Rizk-Jackson(a)ucsf.edu<mailto:Angela.Rizk-Jackson@ucsf.edu> <http://ichs.ucsf.edu/> <https://mail.ucsf.edu/owa/Angela.Rizk-jackson@ucsf.edu/ICHS.ucsf.edu> <applewebdata://B868DB3E-8FDA-4C59-B156-AEA5C76C0163/UrlBlockedError.aspx> ICHS.ucsf.edu<http://ichs.ucsf.edu/> <http://ichs.ucsf.edu/>

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