March 2019 - compbio-allhands@cgl.ucsf.edu

[Compbio-allhands] Yurii Moroz of Enamine visiting Friday April 12th
by John Irwin 28 Mar '19

28 Mar '19

Dear Compbio Allhands If you are or are planning to become Enamine customers, Yurii Moroz, head of the Enamine REAL make-on-demand 710 M and growing project will be visiting us in two weeks, Friday April 12. He will be visiting with one or two colleagues. If you would like to meet Yurii, please write me with a time that works for you and I will try to arrange. Yurii will hold "Office Hours" in BH501 from 11-12 and 3-4 pm where you may simply drop by to chat. If you plan to do this, please let me know in a one-line email so we can plan. John John Irwin UCSF Pharmaceutical Chemistry http://irwinlab.compbio.ucsf.edu

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[Compbio-allhands] Fwd: postdoc positions
by Andrej Sali 28 Mar '19

28 Mar '19

> Begin forwarded message: > > From: Pedro Beltrao <pbeltrao(a)ebi.ac.uk> > Subject: postdoc positions > Date: March 28, 2019 at 4:13:26 AM PDT > To: undisclosed-recipients:; > > Dear colleagues, > > I am currently recruiting for 2 funded bioinformatics postdoc positions and I would be grateful if you could forward this to members of your team that may be a fit to such a position. > > We are hiring for any topic that relates to the interest of the group. This includes large scale studies of phosphorylation/ubiquitination and mutation data and/or genotype to phenotype analysis, including cancer genomics. Bioinformatics experience is required but I would also welcome applications for combined wet/dry positions. > > https://www.embl.de/jobs/searchjobs/index.php?ref=EBI01381&newlang=1&pos[]=… <https://www.embl.de/jobs/searchjobs/index.php?ref=EBI01381&newlang=1&pos[]=…> > > Although the closing date is on the 18 of April, I am happy to wait for strong applicants to join later in the year or even at the start of next year. > > thank you in advance > Pedro

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[Compbio-allhands] 4/4/19 Seminar with Zan Luthey-Schulten
by Flowers, Nicole 26 Mar '19

26 Mar '19

BBC Graduate Programs Seminar Series Bioinformatics Biophysics Chemistry & Chemical Biology Complex Biological Systems Thursdays, 12 Noon Genentech Hall Auditorium Livestream: http://tiny.ucsf.edu/TATvuI Zan Luthey-Schulten University of Illinois at Urbana-Champaign Towards Simulating a Minimal Bacterial Cell: Integration of Experiment and Theory April 4, 2019 W. Marshall, Host BBC Seminars are supported by the Biophysics, Bioinformatics, and Chemistry & Chemical Biology IFM, Department of Pharmaceutical Chemistry, QBC, HARC Center, and the Center for Systems and Synthetic Biology, and the Gladstone Center for Cell Circuitry. -- Nicole Takesono Flowers BMI, BP, CCB, & PSPG Graduate Program Assistant UCSF MC 2280 600 16th St. Genentech Hall Room 522 San Francisco, CA 94143 P: 415.502.6518

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[Compbio-allhands] Schrodinger software workshop @ UCSF - April 11
by John Irwin 13 Mar '19

13 Mar '19

Please register to reserve your spot! (free) https://www.eventbrite.com/e/schrodinger-workshop-at-uc-san-francisco-regis… Morning Session: Life-Sciences Molecular Dynamics Time: 9:30am - 12:00pm Description: This workshop is designed to enable users to run protein molecular dynamics simulations effectively using best practices. We cover basic workflows which include how to build systems appropriate for MD, running MD, basic and advanced trajectory analysis tools, and the architecture and configuration of Desmond input and output files. Finally, we will consider the use of binding-pose metadynamics as an approach for improved pose prediction within the context of a protein-ligand complex. Familiarity with Maestro is recommended. More details on MD can be found at: https://www.schrodinger.com/desmond Afternoon Session: Compound Library Preparation and Ligand-based Virtual Screening Time: 1:00pm - 3:30pm Description: This half-day workshop will cover two interrelated toolsets in computer-aided drug design that rely on the use of chemical descriptors to shape and screen compound libraries. The first part of the workshop will cover compound library design and preparation for virtual screening. During the session, we will discuss the selection and enumeration of virtual compound libraries followed by the shaping and preparation of those libraries for virtual screening. Hands-on tutorials with Schrödinger’s enumeration and filtering tools will be provided. The second part of the workshop will be an introduction to pharmacophore-based virtual screening with Schrödinger’s Phase. More details on Phase can be found at: https://www.schrodinger.com/phase John Irwin UCSF Pharmaceutical Chemistry http://irwinlab.compbio.ucsf.edu

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[Compbio-allhands] 10 am TODAY seminar: Design and synthesis of novel building blocks for drug discovery
by John Irwin 13 Mar '19

13 Mar '19

Seminar by Pavel Mykhailiuk, CSO Enamine, Kyiv "Design and synthesis of novel building blocks for drug discovery." Genentech Hall S-536A Weds March 13, 2019, 10-11 am TODAY Host: John Irwin John Irwin UCSF Pharmaceutical Chemistry http://irwinlab.compbio.ucsf.edu

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[Compbio-allhands] Seminar: Pavel Mykhailiuk of Enamine - Weds March 13 2019 . 10 am
by John Irwin 11 Mar '19

11 Mar '19

Seminar by Pavel Mykhailiuk, CSO Enamine, Kyiv "Design and synthesis of novel building blocks for drug discovery." Genentech Hall S-536A Weds March 13, 2019, 10-11 am Host: John Irwin

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[Compbio-allhands] 3/14/19 Seminar with Rachel Klevit
by Flowers, Nicole 08 Mar '19

08 Mar '19

BBC Graduate Programs Seminar Series Bioinformatics Biophysics Chemistry & Chemical Biology Complex Biological Systems Thursdays, 12 Noon Genentech Hall Auditorium Livestream: http://tiny.ucsf.edu/VB1vGc Rachel Klevit Yale From One to Many: How Ubiquitin Regulates (almost) Everything March 14, 2019 S. Dickinson, Host BBC Seminars are supported by the Biophysics, Bioinformatics, and Chemistry & Chemical Biology IFM, Department of Pharmaceutical Chemistry, QBC, HARC Center, and the Center for Systems and Synthetic Biology, and the Gladstone Center for Cell Circuitry. -- Nicole Takesono Flowers BMI, BP, CCB, & PSPG Graduate Program Assistant UCSF MC 2280 600 16th St. Genentech Hall Room 522 San Francisco, CA 94143 P: 415.502.6518

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[Compbio-allhands] Fwd: Fall ACS Meeting - Call for abstracts - Women make COMP symposium
by Jacobson, Matt 05 Mar '19

05 Mar '19

— Matt Begin forwarded message: From: "Armacost, Kira A." <kira.armacost(a)merck.com<mailto:kira.armacost@merck.com>> Subject: Fall ACS Meeting - Call for abstracts - Women make COMP symposium Date: March 5, 2019 at 11:18:55 AM PST Cc: Giulia Palermo <gpalermo(a)engr.ucr.edu<mailto:gpalermo@engr.ucr.edu>>, Maria Nagan <maria.c.nagan(a)gmail.com<mailto:maria.c.nagan@gmail.com>> Hey all – This is a call for the Women make COMP symposium that will be held at the Fall ACS meeting in San Diego. We are actively searching for abstracts from female graduate students and postdocs to participate in this symposium. Each awardee will be given the opportunity to present a short oral presentation alongside lectures from eminent women in the COMP field from both academia and industry. The awardee will also be given the Promise in COMP award, which includes registration fees and a plaque. Abstracts are due March 25th, under the ACS MAPS portal for COMP – Women make COMP symposium. Please see attached PDF for any other information, and forward to whomever you would like. If you have any questions, please let myself, Giulia or Maria know! Thanks, Kira Armacost Notice: This e-mail message, together with any attachments, contains information of Merck & Co., Inc. (2000 Galloping Hill Road, Kenilworth, New Jersey, USA 07033), and/or its affiliates Direct contact information for affiliates is available at http://www.merck.com/contact/contacts.html) that may be confidential, proprietary copyrighted and/or legally privileged. It is intended solely for the use of the individual or entity named on this message. If you are not the intended recipient, and have received this message in error, please notify us immediately by reply e-mail and then delete it from your system.

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compbio-allhands March 2019