- compbio-allhands@cgl.ucsf.edu - RBVI Mailing Lists

[Compbio-allhands] 10/8/20 BBC Seminar with Cole Trapnell, PhD
by Flowers, Nicole 08 Oct '20

08 Oct '20

BBC Graduate Programs Seminar Series Bioinformatics Biophysics Chemistry & Chemical Biology Complex Biological Systems Thursdays, Noon Zoom: http://tiny.ucsf.edu/XsDVET Cole Trapnell, Ph.D. University of Washington Embryo scale single-cell spatial transcriptomics October 8, 2020 S. Bandyopadhyay, Host BBC Seminars are supported by the Biophysics, Bioinformatics, and Chemistry & Chemical Biology IFM, Department of Pharmaceutical Chemistry, QBC, HARC Center, the Center for Systems and Synthetic Biology, and the Gladstone Center for Cell Circuitry. Subscribe to the BBC Seminar Series Calendar! Use this URL to access this calendar from a web browser.<https://urldefense.proofpoint.com/v2/url?u=https-3A__calendar.google.com_ca… > Use this address to access this calendar from other applications.<https://urldefense.proofpoint.com/v2/url?u=https-3A__calendar.google.com_ca… > Use this URL to view the calendar in iCal.<https://urldefense.proofpoint.com/v2/url?u=https-3A__ucsf.us20.list-2Dmanag…> -- Nicole Takesono Flowers she/her/hers Biophysics Graduate Program Manager UCSF MC 2240 600 16th St. Genentech Hall Room N474D San Francisco, CA 94143 P: 415.502.6518

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[Compbio-allhands] 10/15/20 Seminar with Nicholas Ball, PhD, Noon
by Flowers, Nicole 07 Oct '20

07 Oct '20

Seminar with Nicholas D. Ball, PhD Pomona College Synthetic strategies toward fluorosulfurylation of organic molecules & sulfer-fluoride exhange (SUFEX) Thursday, October 15, 2020 Noon Danica Galonic Fujimori, Host 415.514.0147 danica.fujimori(a)ucsf.edu<mailto:danica.fujimori@ucsf.edu> https://urldefense.proofpoint.com/v2/url?u=https-3A__ucsf.zoom.us_j_9995012… <https://urldefense.proofpoint.com/v2/url?u=https-3A__ucsf.zoom.us_j_9995012… > Meeting ID: 999 5012 2338 Password: 590025 -- Nicole Takesono Flowers she/her/hers Biophysics Graduate Program Manager UCSF MC 2240 600 16th St. Genentech Hall Room N474D San Francisco, CA 94143 P: 415.502.6518

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[Compbio-allhands] Fwd: Invitation | Sir Ernst Chain Lecture 2020 | 4 November 2020: Enzymes, evolution and disease: 50 years of Bioinformatics Prof Dame Janet Thornton
by Andrej Sali 07 Oct '20

07 Oct '20

> Begin forwarded message: > > From: "Sternberg, Michael J E" <m.sternberg(a)imperial.ac.uk> > Subject: FW: Invitation | Sir Ernst Chain Lecture 2020 | 4 November 2020: Enzymes, evolution and disease: 50 years of Bioinformatics Prof Dame Janet Thornton > Date: October 7, 2020 at 9:48:31 AM PDT > > > Dear Colleague > > You may wish to attend and/or advertise to your colleagues this virtual talk. > > Best > > Mike > --------------------------------------- > > > > > The honour of your company is requested at the Sir Ernst Chain Lecture 2020: > > Enzymes, Evolution and Disease: 50 years of bioinformatics > Professor Dame Janet Thornton, FRS, FMedSci, EMBL-EBI > > Date: Wednesday 4 November 2020 > Time: 17:00 – 18:30 GMT > Venue: Microsoft Teams Live Event > > The lecture is free to attend and open to all, but registration is required in advance. > Register to attend on Eventbrite <https://www.eventbrite.co.uk/e/sir-ernst-chain-lecture-2020-enzymes-evoluti…> > The link to join the event will be circulated in the joining instructions > > Abstract > The last 50 years have seen bioinformatics evolve from a relatively minor pursuit into one of the major areas of biological research today. This has been driven by the DNA sequencing revolution and the rise of structural biology, which was only just beginning 50 years ago. Some of the first protein structures were of enzymes and were determined in Oxford – a prelude to understanding how they functioned as catalysts and performed their biological function. Today we have garnered data on almost 1000 enzymes, whose structures and functions are known, to improve our understanding of biocatalysis. One surprising finding has been that most enzymes have evolved from other ‘older’ enzymes, by slight modification of the binding sites or occasionally the catalytic mechanism. Another is that many diseases occur because of single amino acids variants which affect enzyme function. Even ageing can be modulated by single variants. These variants are gradually being identified and understood in terms of their effects on health, diseases and ageing. > > Despite all these data, biology remains in a ‘discovery phase’, where there are many many basic facts we still do not know or do not understand about how living organisms work. However, in parallel we now see an increasing push to exploit this flood of data to improve the world we live in. Bioinformatics provides the glue and the analytical approaches to develop quantitative models of life, which in the clinic can potentially help in diagnosis, prognosis and even sometimes identify a therapy. It is clear that the next 50 years will see the emergence of robust mathematical models to characterize living processes and make predictions. The relatively recent emergence of machine learning and synthetic biology have further fuelled the possibilities to harness all this molecular data for the benefit of society – addressing some of our major societal issues like infectious diseases, antimicrobial resistance and designing green waste disposal. > > The lecture will highlight the contributions of bioinformatics over the last 50 years and provide a glimpse of future opportunities. > > Biography > Janet Thornton is a Senior Scientist at the European Molecular Biology Laboratory’s European Bioinformatics Institute (EMBL-EBI) on the Wellcome Genome Campus at Hinxton, near Cambridge, UK. She was Director of the Institute from 2001-2015. > > She studied for her PhD at the National Institute for Medical Research at Mill Hill after graduating as a physicist. After a post-doc in Oxford, Janet moved to London (Birkbeck and later UCL) before becoming Director at EMBL-EBI. Janet’s research is focused on proteins, especially their structure, function and evolution. She is a computational biologist, working at the interface of biology with physics, chemistry, and computing. This includes a detailed analysis of enzyme biocatalysts, their mechanisms and the evolution of new functions. Her group is also investigating the molecular basis of ageing. She has published more than 500 scientific papers, was elected to the Royal Society in 1999 and is a Foreign Associate of US National Academy of Sciences. In 2012 she became a Dame Commander of the Order of the British Empire for services to bioinformatics. > > Please note that Imperial College London processes your personal data in line with the Advancement Privacy Notice. <http://www.imperial.ac.uk/advancement/about-us/advancement-policies/privacy…> If you have any questions or concerns about this, please contact events(a)imperial.ac.uk <mailto:events@imperial.ac.uk>

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[Compbio-allhands] 9/24/20 BBC Seminar with Allison Williams, PhD
by Flowers, Nicole 28 Sep '20

28 Sep '20

BBC Graduate Programs Seminar Series Bioinformatics Biophysics Chemistry & Chemical Biology Complex Biological Systems Thursdays, Noon Zoom: http://tiny.ucsf.edu/nhyH2x Allison Williams, Ph.D. UCSF Kickoff Lecture: Unravelling the mechanism of activation of the bacterial stress signaling platform September 24, 2020 J. Fraser, Host BBC Seminars are supported by the Biophysics, Bioinformatics, and Chemistry & Chemical Biology IFM, Department of Pharmaceutical Chemistry, QBC, HARC Center, the Center for Systems and Synthetic Biology, and the Gladstone Center for Cell Circuitry. -- Nicole Takesono Flowers she/her/hers Biophysics Graduate Program Manager UCSF MC 2240 600 16th St. Genentech Hall Room N474D San Francisco, CA 94143 P: 415.502.6518

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Re: [Compbio-allhands] 10/1/20 BBC Seminar with Margaret Gardel, PhD
by Flowers, Nicole 25 Sep '20

25 Sep '20

BBC Graduate Programs Seminar Series Bioinformatics Biophysics Chemistry & Chemical Biology Complex Biological Systems Thursdays, Noon Zoom: http://tiny.ucsf.edu/nORVLJ Margaret Gardel, Ph.D. University of Chicago Cytoskeletal Mechanosensing by LIM domains October 1, 2020 D. Mullins, Host BBC Seminars are supported by the Biophysics, Bioinformatics, and Chemistry & Chemical Biology IFM, Department of Pharmaceutical Chemistry, QBC, HARC Center, the Center for Systems and Synthetic Biology, and the Gladstone Center for Cell Circuitry. Subscribe to the BBC Seminar Series Calendar! Use this URL to access this calendar from a web browser.<https://urldefense.proofpoint.com/v2/url?u=https-3A__calendar.google.com_ca… > Use this address to access this calendar from other applications.<https://urldefense.proofpoint.com/v2/url?u=https-3A__calendar.google.com_ca… > -- Nicole Takesono Flowers she/her/hers Biophysics Graduate Program Manager UCSF MC 2240 600 16th St. Genentech Hall Room N474D San Francisco, CA 94143 P: 415.502.6518

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[Compbio-allhands] 10/1/20 BBC Seminar with Margaret Gardel, PhD
by Flowers, Nicole 25 Sep '20

25 Sep '20

BBC Graduate Programs Seminar Series Bioinformatics Biophysics Chemistry & Chemical Biology Complex Biological Systems Thursdays, Noon Zoom: http://tiny.ucsf.edu/nORVLJ Margaret Gardel, Ph.D. University of Chicago Cytoskeletal Mechanosensing by LIM domains October 1, 2020 D. Mullins, Host BBC Seminars are supported by the Biophysics, Bioinformatics, and Chemistry & Chemical Biology IFM, Department of Pharmaceutical Chemistry, QBC, HARC Center, the Center for Systems and Synthetic Biology, and the Gladstone Center for Cell Circuitry. Subscribe to the BBC Seminar Series Calendar! Use this URL to access this calendar from a web browser.<https://urldefense.proofpoint.com/v2/url?u=https-3A__calendar.google.com_ca… > Use this address to access this calendar from other applications.<https://urldefense.proofpoint.com/v2/url?u=https-3A__calendar.google.com_ca… > -- Nicole Takesono Flowers she/her/hers Biophysics Graduate Program Manager UCSF MC 2240 600 16th St. Genentech Hall Room N474D San Francisco, CA 94143 P: 415.502.6518

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[Compbio-allhands] Fwd: Program Officer Position at CPP Branch NIDA NIH
by Brian Shoichet 22 Sep '20

22 Sep '20

FYI Brian Shoichet, Professor, UCSF latest science http://www.bkslab.org ---------- Forwarded message --------- From: Ananthan, Sam (NIH/NIDA) [E] <sam.ananthan(a)nih.gov> Date: Tue, Sep 22, 2020, 7:26 PM Subject: Program Officer Position at CPP Branch NIDA NIH To: shoichet(a)cgl.ucsf.edu <shoichet(a)cgl.ucsf.edu> Dear Dr. Shoichet, I recently joined NIDA and am writing to request your help. We have an opening for a Program Officer position in the Chemistry, Pharmacology, and Physiology Branch of NIDA/NIH. I would appreciate it very much if you could inform people from your group/organization who might be interested in applying for the position. The application deadline is September 30. The following is the link: https://www.usajobs.gov/GetJob/ViewDetails/578944200 Thanks. With best regards, Sam *Sam Ananthan, Ph.D.* *Chief, Chemistry and Pharmacology Branch* *Division of Neuroscience and Behavior* *National Institute on Drug Abuse* *National Institutes of Health* *North Bethesda, MD 20852* *Phone: 301-435-2199* *Cell: 301-204-2889* *Email: sam.ananthan(a)nih.gov <sam.ananthan(a)nih.gov>*

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[Compbio-allhands] Fwd: [3dem] Data curation post for EMDB and EMPIAR
by Andrej Sali 17 Sep '20

17 Sep '20

> Begin forwarded message: > > From: Ardan Patwardhan <ardan(a)ebi.ac.uk> > Subject: [3dem] Data curation post for EMDB and EMPIAR > Date: September 17, 2020 at 1:20:30 AM PDT > To: 3dem(a)ncmir.ucsd.edu > > Dear all > > We have a post opening at EMBL-EBI, Hinxton UK to work on EMDB and EMPIAR data curation at a very exciting time when the archives are expanding rapidly both in volume and richness of content: https://www.embl.de/jobs/searchjobs/index.php?ref=EBI01684&newlang=1&pos%5B… <https://urldefense.com/v3/__https://www.embl.de/jobs/searchjobs/index.php?r…> > > Many thanks and best wishes > > Ardan > > Ardan Patwardhan > Team Leader - Cellular Structure & 3D Bioimaging > EMDB & EMPIAR > European Bioinformatics Institute (EMBL-EBI) European Molecular Biology Laboratory > Wellcome Trust Genome Campus > Hinxton, Cambridge CB10 1SD > _______________________________________________ > 3dem mailing list > 3dem(a)ncmir.ucsd.edu > https://mail.ncmir.ucsd.edu/mailman/listinfo/3dem

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[Compbio-allhands] Fwd: junior position in theoretical structural biology
by Andrej Sali 09 Sep '20

09 Sep '20

> Begin forwarded message: > > From: Juri Rappsilber <Juri.Rappsilber(a)TU-Berlin.de> > Subject: junior position in theoretical structural biology > Date: September 9, 2020 at 6:56:35 AM PDT > To: "Rappsilber, Juri" <juri.rappsilber(a)tu-berlin.de> > > Hi * > > TU Berlin is looking for a junior group leader in theoretical structural biology. Deadline is extended to end of the month. If you know any candidates, please, let them know. Please also post in networks. > > All the best, > > Juri >

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[Compbio-allhands] Fwd: Foghorn Therapeutics is looking to hire a Computational Chemist
by Jacobson, Matt 27 Aug '20

27 Aug '20

Another job opening — Matt Begin forwarded message: From: Tori Caldwell <tcaldwell(a)foghorntx.com<mailto:tcaldwell@foghorntx.com>> Subject: Foghorn Therapeutics is looking to hire a Computational Chemist Date: August 26, 2020 at 8:27:21 AM PDT To: "Matt.Jacobson(a)ucsf.edu<mailto:Matt.Jacobson@ucsf.edu>" <Matt.Jacobson(a)ucsf.edu<mailto:Matt.Jacobson@ucsf.edu>> Hi Matt, I am working with Johannes Voigt, one of our hiring managers, who is looking to hire a Computational Chemist – from Scientist to Principal Scientist level (ligand design and data analysis, not machine learning). We are fine with hiring someone junior. As a well-known leader in this space, I wanted to ask if you happen to know anyone who may be looking or have any suggestions on where I can find them or post the opening. We would really appreciate any and all help. Here is a link to the job - https://urldefense.proofpoint.com/v2/url?u=https-3A__foghorntx.com_careers_… <https://urldefense.proofpoint.com/v2/url?u=https-3A__foghorntx.com_careers_…> Thank you in advance for your time. Best, Tori Tori Caldwell| Director, Talent Acquisition and Culture tcaldwell(a)foghorntx.com<mailto:tcaldwell@foghorntx.com> Mobile: 617.949.5500 100 Binney Street, Suite 610 | Cambridge, MA 02142 [cid:image001.png@01D67B96.21BA32D0]

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