Hi Everyone,
Despite not really being qualified, I’ve done several protein modeling workshops at universities over the past year with some positive responses. It seems to be quite useful to a good number of scientists like myself (clueless molecular/cellular biologists etc), and in particular for less experienced users. Part of my ability to pull this off at any level has been the help I’ve received from others including the wonderful staff the ChimeraX, who I give ample props to in the video.
Anyway, feel free to share with students or others who might find this useful. It’s rather long (97 minutes) and I do go into a fair bit of detail about how ipTM is determined along with some of the recently developed alternative metrics for scoring protein-protein interactions. I’ve attached the link below. I also realize that this user group is very sophisticated, so feel free to comment or correct and to add to anything I may have missed or not stated properly.
Thanks and happy new year,
David
David S. Fay Ph.D.
Professor, Department of Molecular Biology
Director (PD/PI), National Institutes of Health Wyoming INBRE
University of Wyoming
email: davidfay(a)uwyo.edu<mailto:davidfay@uwyo.edu>
<https://youtu.be/u63oYfWDBoM>
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David's AlphaFold WorkShop 2026<https://youtu.be/u63oYfWDBoM>
youtu.be<https://youtu.be/u63oYfWDBoM>
Happy New Year to all
I’m unable to find out how to obtain Boltz binding affinity predictions. Probably, I’m missing out something. Any help would be most welcome. I’m attaching a screenshot for easy diagnostics.
Many thanks
